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Bryophyllum pinnatum is used as traditional medicine in India, Africa, Tropical America and China for treatment of various diseases. (Crassulaceae), Assessment of the medical benefit in the folkloric use of Bryophyllum Pinnatum leaf among the Igbos of Nigeria for the treatment of hypertension, Kalanchoe pinnata: Phytochemical and pharmacological profile, Mechanisms Underlying the Antinociceptive, Antiedematogenic, and Anti-Inflammatory Activity of the Main Flavonoid from Kalanchoe pinnata, Pharmacognostical Studies of Bryophyllum pinnatum (Lam.) Aloe Vera: The Miracle Plant Its Medicinal and Traditional Uses in India, Antimicrobial Activity of Leave Extracts of Bryophyllum pinnatum and Aspilia africana on Pathogenic Wound Isolates Recovered from Patients Admitted in University of Port Harcourt Teaching Hospital, Nigeria, Chemical Constituents Analysis of the Leaves of Bryophyllum pinnatum by GC-MS, African Journal of Pharmacy and Pharmacology Antidiabetic potential of ethanol leaf extract of Bryophyllum pinnatum on alloxan-induced diabetic rats and their haematological profiles, Bufadienolides of Kalanchoe species: an overview of chemical structure, biological activity and prospects for pharmacological use, Gastroprotective activity of the hydroethanolic extract and ethyl acetate fraction from Kalanchoe pinnata (Lam.) Bryophyllum pinnatum (Lam.) The results revealed the presence of bioactive constituents comprising alkaloids (1.24 to 1.48 mg/100 g), saponins (1.46 to 1.72 mg/100 g), flavonoids (1.46 to 1.86 mg/100 g), phenols (0.06 mg/100g) and tannins (0.04 to 0.5 mg/100g). : A Review, Transaminase compared with cholinesterase and alkaline phosphatase an index of hepatocellular integrity, Medicinal plants of Muzaffarnagar district used in treatment of urinary tract and kidney stones, Establishment of correlation between in-silico and in-vitro test analysis against Leishmania HGPRT to inhibitors, In-vitro cytotoxicity and Phytochemical Activity in Bryophyllum pinnatum, Current Trends and Future Prospects of Lipstatin: A Lipase Inhibitor and Pro-Drug for Obesity, Anti-inflammatory activity of the leaf extracts/fractions of Bryophyllum pinnatum Saliv.Syn, Anti-inflammatory action of Bryophyllum pinnatum leaf extract, Evaluation of the chemical composition of two Nigerian medicinal plants, Importance of coriander (Coriandrum sativum L.) between the medicinal and aromatic plants, Evaluation of Anticonvulsant Potential of Bryophyllum pinnatum in Experimental Animals, Investigation of Cytotoxicity and Antifungal Activities of Petroleum Ether and Aqueous Extracts of Leaves and Stems of Kalanchoe pinnata L. (Crassulaceae), Evaluation of the in vitro combined antibacterial effect of the leaf extracts of Bryophyllum pinnatum (Fam: crassulaceae) and Ocimum gratissimum (Fam: labiatae), Activity of Bryophyllum pinnatum S. Kurz extracts on respiratory tract pathogenic bacteria, Evaluation of chemical composition of indeginous species and flavouring agents, Gastroprotective effect of aqueous extract and mucilage from Bryophyllum pinnatum (Lam.) Parameters observed in MES model were duration of hind limb tonic extension (HLTE), the total recovery time and percentage protection. 3 0 obj
The administration of the crude leaf extract of the plant along with high fat diet reduced the high fat diet induced increases in serum liver and kidney cholesterol levels in rats (Ghasi et al., 2000). In the present study the petroleum ether and aqueous extracts of the leaves and stems of the plant were used to investigate the cytotoxicity and antifungal activities using brine shrimp lethality bioassay and agar disc diffusion method, respectively. In ethanol induced ulcer rats, there was a decrease in the gastric volume, free and total acidity and ulcerative index as compared to the control group. The plant is also used as food material. Kalanchoe pinnata L. (Crassulaceae) has traditionally been used in Bangladesh as medicinal plant for the treatment and prevention of different diseases. The plant shows biological activities such as antiviral and antimicrobial properties. Methanolic extract showed highest activity. >>
A review of some important patents on Cynodon dactylonis presented. Phenytoin 25mg/kg was used as the standard drug in the MES model and in the PTZ model Diazepam 4mg/kg was used. Family Crassulaceae Common Names air plant, airplant, Canterbury bells, cathedral bells, curtain plant, floppers, good luck leaf, green mother … 1 0 obj
Saraca asoca is reported to contain glycoside, flavanoids, tannins and saponins. markedly decrease the incidence of ulcers in ethanol induced ulcer rats. endobj
Materials and Methods: Antioxidant and free radical scavenging activity was determined by using five different in vitro antioxidant assays including 2, 2-Diphenyl-1-Picrylhydrazyl (DPPH), hydrogen peroxide, nitric oxide, ferric reducing antioxidant power and phosphomolybdenum assays. The present study was carried out to evaluate the gastroprotective activity of B. pinnatum whole plant aqueous extract, and mucilage (MUC) isolated from the whole plant against ethanol induced gastric ulcer. plant is found naturally throught the country. The medicinal and aromatic plants are an accessible, affordable and culturally appropriate source of primary health care for more than 80% of world's population. ఎవ్వరూ మిస్ అవ్వద్దు ! In ethnomedicine, it is known for its anthroposophical and tocolytic effects in pregnant women. or hepatotoxicity example Bryophyllum pinnatum is a medicinal plant that possess strong antioxidant activities which are flavonoids, polyphanols, alkaloids, saponins, vitamins (A,C,E & K), carotemoids, minerals, enzymes (glutathione peroxidase), lignins, xanthone and pigment. A recombinant protein has 24 kDa molecular mass (rLdHGPRT) was cloned, expressed and purified for testing of guanosine monophosphate (GMP) analogous compounds invitro by spectroscopically to the rLdHGPRT, Lysates protein and MTT assay on Leishmania donovani. The Creoles use the lightly roasted leaves for cancer, inflammations, and a leaf infusion for fevers. Extract was used in 200, 300 and 400 mg/kg doses. tailored to confer physiological and health benefits that go beyond their nutritional function. Moreover, the petroleum ether and aqueous extracts of Kalanchoe pinnata L. were investigated for their antifungal activity against six fungal strains and the results (diameter of zone of inhibition) were compared with the activity of the commercially available standard drug, Griseofulvin (30 jug disc -1). It is a widely growing perennial herb and used in medicine with Objectives: To study the effect of Bryophyllum pinnatum (Lam.) Bryophyllum pinnatum (Lam.) Methodology: The leaves of BP were... | Find, read and … Among the different fractions (Hexane, chloroform, acetone and methanol) tested for antimicrobial activity, the non-polar fractions were more active than the polar fractions. A binding study suggests that one molecule of lipstatin binds with one molecule of lipase. <>
Phytochemical screening was also carried out according to the standard procedures. >>
The petroleum ether and aqueous extracts of Kalanchoe pinnata L. (80 jug disc -1) showed moderate activity against all tested fungal strains with zones of inhibition ranging from 1,5Q±0.00 mm to 2.67±0.24 mm and 1.67±0.24 mm to 2.83±0.24 mm, respectively. Consumer demands and acceptance in terms of consumption patterns, ethnicity, culture, religion, and allergy, amongst others, need to be taken into consideration when choosing appropriate vehicles for functional food development.Keywords: food vehicles, functional foods, food fortification, food choice, food preference, fortification, phytonutrients, bioactive compounds. In brine shrimp lethality bioassay, the LC 50 (jug mL -1) andLC 90 (fig mL -1) of the petroleum ether extract of Kalanchoe pinnata L. were 25.12 jag mL 1 and 177.83 jug mL -1, respectively. It is commonly known as Zakham-e-hyat, Cathedral bells, air or maternity plant, love plant, Life plant, Canterbury bells and also parnabija. The fresh leaves of air plant can also be eaten raw as a medicinal remedy for asthma, bronchitis and intestinal problems. It is used for rheumatoid arthritis, bruises, burns and ulcers in China. The n-hexane soluble fraction was subjected to activity guided column chromatography. Cynodon dactylon (L.) Pers. All the decimal combinations of BPME/OGWE, BPME/OGWE and OGWE yielded synergistic effects test bacteria. have been evaluated. Bryophyllum pinnatum is widely used in Ayurvedic system of the medicine as astringent.the plant is widely use in traditional medicine for treatment of various ailments and well known for its haemostatic and wound healing properties.it is an indigenous and exotic plant. : Phytochemical and pharmacological profile: A review, New Bufadienolides from Kalanchoe daigremontiana Hamet et Perr. They are green with purple serrated margins which are … petroleum ether, alcohol and water on healing of excision, resutured incision and . The … Our review indicated some foods to be considered as potential immune enhancers, which may help individuals to overcome viral infections like COVID-19 by modulating immune systems and reducing respiratory problems. Moreover, several polyphenols extracted from pomegranate inhibited the invasion potential, migration and viability of breast cancer cells. and MUC at dose of 500 mg/kg p.o. Scientists have explored the different parts of the plant and have established the clinical potentials of the plant as a whole and its parts successfully. The decoction of the leaves of the plant Bryophyllum pinnatum along with Aegle marmelos (Bilwa) is given to treat dysentery in a dosage of 30-40 ml in divided dose. The information on medicinal uses is based on the exhaustive interviews with local healers and herbalists, practicing traditional system of medicine. Furthermore, this review will provide information regarding biological properties of conventional foods and their ingredients to uphold general health. Lipids are known to produce more energy than sugars and proteins, hence controlling the digestion of dietary lipids is a promising approach to treat obesity. Experimental studies have shown numerous pharmacological properties, including antimicrobial, antiplasmodial, anti-trypanosomal, anti-leishmanial, anti-nematicidal, anti-inflammatory, anti-oxidant, antidiabetic and other activities. These inhibitions were statistically significant (p<0.05-0.01, 0.001) as compared to control. Tweet on Twitter. Immunological Effects of Medicinal Plants: A review (part 2). Kurz, The miracle plant (Kalanchoe pinnata): A phytochemical and pharmacological review, Biological role of Piper nigrum L. (Black pepper): A review, Review of natural products with hepatoprotective effects, Comparative Study of Nutritional and Phytochemical Attributes of Andrographis paniculata, Bryophyllum pinnatum and Clitoria ternatea for Nutraceutical Applications, Inhibitory effect of Bryophyllum pinnatum (Lam.) The aqueous whole plant extract of B. pinnatum at dose of 750 mg/kg showed a significant reduction in the above parameters which was comparable to the standard drug rabeprazole (20 mg/kg). Conclusion: This review article provides comprehensive information on S. spinosa and its various extracts. & Schweinf. Obesity is an alarming state caused by an energy imbalance. PDF | Aims: To identify extractable components in the traditional medicinal plant, Bryophyllum pinnatum (BP). Uses of Parnabeeja – Bryophyllum pinnatum. Pers. nY��[�y�vv]�k��������7��4ͧC�ץ���'��o��⡄�_"L���c"N��g$N�� ���U9�0�S\�ql������_�#�U��3�V+���^�j���ɻ;��N{�QRN8�b@���N�@b�^(b��X2s�Bzf��)�\BBg��'���������(��i���|���� F��R+�g�"�Tkm{3��lE�~��$�iW�ֆl[ �X˙AG? Kurz (Crassulaceae) is a perennial herb growing widely and used in folkloric medicine in tropical Africa, tropical America, India. 5 0 obj
Heated leaves used for swellings and abscesses in Jamaica. Kurz. Interestingly, LdHGPRT complex has showed stable after 24ns in molecular dynamics simulation with interacting amino acids are Glu125, Ile127, Lys87 and Val186. It grows wildly in Madagascar and Jamaica. Oken Synonyms Bryophyllum calycinum Salisb. The extracts/fractions inhibited formaldehyde-induced paw edema in rats. The plant is a rich source of metabolites such as proteins, carbohydrates, mineral constituents, P-sitosterol, flavanoids, alkaloids, glycosides and triterpenoides. Cotyledon calyculata Sol. This study provides a comprehensive detail of the pharmacognostical characteristics, biological effects and medicinal uses of Cynodon dactylon. Astringent is generally used as an application for cleansing, but before moisturizing. 4 0 obj
Objective: Bryophyllum pinnatum (Lam.) Due to the promising effects of the plant extracts on various diseases and its nutritional values, there is a need for toxicity studies and clinical trials to assess the effects of its identified bioactive compounds. The extracts showed significant antioxidant activity in dose dependent manner in all the assays. Lipstatin is a β-lactone molecule which controls the digestive activity of pancreatic lipases and thus controls the absorption of fat in the small intestine. The medicinal and aromatic plants have been an integral part of our daily life for thousands of years. Results: Among these plants, Cordia oblique (chloroform extract) and Croton bonplandianum (Hexane extract), which showed superior antimicrobial activity in the primary screening test. Bryophyllum pinnatum paste is used for the treatment of boil, wound, soar or cuts. The three dimensional structure of pancreatic lipase revealed that its active site is masked by a lid domain which is opened by the action of bile salt micelles and colipase. Today, public desire for community has increased the use of medicinal plants are the reasons become more wealthy societies, changes in the culture of nutrition, to show the destructive effects of chemical drugs, increased use of trust in communities and industrial plants and environmental pollution; so that the use of plants is important in most developed countries as a norm for health. There are several mechanistic studies in mouse models and in breast cancer cell lines, suggesting the possible pathways through which polyphenols from pomegranate extracts act, but larger and better-controlled studies are necessary in the future. The mechanism of lipstatin biosynthesis in bacteria is still unexplored. We studied the effects of ethanolic extract of the leaves of Bryophyllum pinnatum against maximal electroshock (MES) induced convulsions and Pentylenetetrazole(PTZ) seizure model in mice. Medicinal use of Patharchatta or Bryophyllum. బంగారం కంటే ఎంతో విలువైన మొక్క ఇదే ! Lipstatin is supposed to inhibit the catalytic activity of pancreatic lipase by acylation of the serine residue present in the active site. S. spinosa contains many chemical compounds, such as alkaloids, terpenes, sterols, fatty acids, flavonoids, saponin, and others. In the KwaZulu-Natal Province, South Africa, leaves used in combination with Opuntia stricta and Euphorbia hypericifolia to treat gonorrhea. The activity of this plant’s extracts against the test bacteria coupled with the various phytochemical compounds present in the fractions is a pointer to the plant’s potential as a source of drugs that can be used against respiratory tract pathogens. The 2'deoxyguanosine 5' diphosphate (DGD) (IC50 value 12.5μM) is two times more effective when compared to guanosine-5' diphosphate sodium(GD). It is native to Madagascar and further planted in tropical and subtropical areas around the world. Method: In the present study, methanolic and aqueous extracts of … Our interest in identifying a bioactive compound rich in polyphenols, which induces both the antagonism of the estrogen receptor, and the inhibition of the estrogen synthesis, revealed us the pomegranate fruit and its derivatives: peel and seeds. It is used as spasmogenic, oxytocic, uterotonic, anti-bacterial, anti-implantation, anti-tumour, anti-progestational, anti-estrogenic activity against menorrhagia and anti-cancer. With this Artemisia annua (chloroform extract) showed very remarkable antifungal activity (MIC 0.37 mg/ml) against Aspergillus niger. Oken, Bryophyllum calycinum . These findings indicated that the petroleum ether and aqueous extracts of the plant possessed cytotoxic and antifungal activities. Crassula pinnata L. f. Kalanchoe pinnata (Lam.) Pers, Bryophyllum pinnatum Leaf Extracts Prevent Formation of Renal Calculi in Lithiatic Rats, Bactericide, Immunomodulating, and Wound Healing Properties of Transgenic Kalanchoe pinnata Synergize with Antimicrobial Peptide Cecropin P1 In Vivo, The Chemical Constituents and Pharmacological Effects of Bryophyllum calycinum. Bryophyllum pinnatum (Lam.) 1. Due to it’s content, it could be used in the treatment of liver disease which are mainly caused by toxic … Therefore, body shielding and immune-modulating foods, which have previous scientific recognition, have been discussed in this review to discern the efficacy of these foods against viral infections, especially SARS-CoV-2. The importance of these chemical constituents is discussed with respect to the role of these herbs in ethnomedicine in Nigeria. Kurz. The divine herb contains a wide range of active compounds, including alkaloids, triterpenes, glycosides, flavonoids, steroids, bufadienolides, lipids and organic acids, have been isolated from this … <>
Both clinical and preclinical studies were considered for this review. Relevant scientific literature was electronically sourced from Google Scholar, Google, PubMed, databases of the Journals of Functional Foods in Health and Disease (JFFHD) and Bioactive Compounds in Health and Disease (BCHD) based on their mention or discussion of food choice and preference and food vehicles for food fortification or functional food production. A floristic survey of ethnomedicinal plants was conducted at Muzaffarnagar district of Uttar Pradesh to assess the potentiality of plant resources. <>
Below are given Bryophyllum pinnatum medicinal properties that are used for different ailments. Objective: Our objective of this research work was to investigate antimicrobial activity of five species of traditionally used medicinal plants namely Adhatoda vasica, Artemisia annua, Cordia oblique, Croton bonplandianum and Euphorbia milli against different strains of bacteria and fungi which are known to cause various types of infectious diseases. Our search was performed in the PubMed and Google Scholar databases, and it included only original research written in English from the last 20 years. Few scientific validations have even lead to the isolation and determination of the applications of the bioactive compounds from various solvent extracts of the plant. Uses.Numerous uses have been recorded for Kalanchoe pinnata, in places as widely separated as Africa, India, Brazil, and the West Indies (see Walters, 2011: 243 for references).However, in southern Africa, the species apparently does not feature in traditional medicinal and other uses.
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